Quorum Sensing: It’s About Time
نویسنده
چکیده
Quorum sensing is a form of cell-to-cell communication by which bacteria communicate by secreting signaling molecules called autoinducers that help regulate gene expression. Quorum sensing was first detected in Photobacterium fischeri [1]. A specific acylated homoserine lactone was found to regulate transcription of the luciferase operon resulting in light emission [2]. A related organism, Vibrio harveyi, uses another signaling molecule in addition to an acylated homoserine lactone [3]. This molecule, termed Autoinducer-2 (or AI-2), is a furanosyl borate dieter [4]. AI-2 is also produced and used by a several Gram negative and Gram positive bacteria.
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